San Francisco Bay Area relocation guide
Moving to South San Francisco, CA
$998,500Median listing price
San MateoArea
San Francisco commuteCommute profile
About South San Francisco
South San Francisco ("South City," about 65,000 residents) sits just south of San Francisco on the Peninsula, known as the "Birthplace of Biotechnology" — home to Genentech and a dense cluster of biotech campuses. The giant "SOUTH SAN FRANCISCO THE INDUSTRIAL CITY" hillside sign overlooks a tech community.
Home prices in South San Francisco
The median listing price in South San Francisco is $998,500.
Top places in South San Francisco
- The "SOUTH SAN FRANCISCO THE INDUSTRIAL CITY" hillside sign (city aerial shown in the Commons photo below).
- Genentech campus and the "Birthplace of Biotechnology" gateway signs (shown in the Commons photo below).
- Oyster Point and the bayfront trails.
- Downtown Grand Avenue — shops and restaurants.
- Sign Hill Park — trails around the famous sign.
- Orange Memorial Park and the community civic campus.
Commuting from South San Francisco
- BART: South San Francisco station on the Red/Yellow lines — roughly 20–25 minutes to downtown San Francisco (per BART trip planner ranges).
- Caltrain: South San Francisco station — roughly 25–35 minutes to San Francisco's 4th & King.
- SamTrans bus service.
- Approximate drive to downtown San Francisco via US-101: ~15–30 minutes (longer at peak).
Schools in South San Francisco
Public schools: South San Francisco Unified School District. For enrollment and performance data, see the state report card in Town links below. Confirm school assignment for any address directly with the district.
South San Francisco FAQs
- What is the housing market like in South San Francisco, CA?
The median listing price in South San Francisco is $998,500. Median listing price (September 2026 research snapshot) - How is the commute from South San Francisco, CA?
BART: South San Francisco station on the Red/Yellow lines — roughly 20–25 minutes to downtown San Francisco (per BART trip planner ranges). - Which school district serves South San Francisco, CA?
South San Francisco is served by South San Francisco Unified School District. See the state report card in Town links, and confirm school assignment for a specific address with the district.
Town links
Schools
Transit
Official town resources. School report cards via the National Center for Education Statistics.